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The K562 cell line is a well-established human myelogenous leukemia cell line derived from the pleural effusion of a female patient with chronic myeloid leukemia in blast crisis. These cells are non-adherent and grow in suspension as a round, single-cell population. K562 cells express the Philadelphia chromosome (BCR-ABL fusion gene), making them a valuable model for studying leukemia biology, oncogenic signaling, hematopoiesis, and targeted cancer therapies.
K562 cells have the unique capacity to undergo erythroid, granulocytic, and monocytic differentiation under appropriate stimuli, and are widely used to assess drug responses, immune cell interactions, and gene editing strategies.
The K562 cell line is a well-established human myelogenous leukemia cell line derived from the pleural effusion of a female patient with chronic myeloid leukemia in blast crisis. These cells are non-adherent and grow in suspension as a round, single-cell population. K562 cells express the Philadelphia chromosome (BCR-ABL fusion gene), making them a valuable model for studying leukemia biology, oncogenic signaling, hematopoiesis, and targeted cancer therapies.
K562 cells have the unique capacity to undergo erythroid, granulocytic, and monocytic differentiation under appropriate stimuli, and are widely used to assess drug responses, immune cell interactions, and gene editing strategies.